Haematologica
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Haematologica, Vol 81, Issue 2, 152-154
Copyright © 1996 by Ferrata Storti Foundation

Case Reports

All-trans-retinoic acid and pseudotumor cerebri in a young adult with acute promyelocytic leukemia: a possible disease association

G Visani, G Bontempo, S Manfroi, A Pazzaglia, R D'Alessandro, and S Tura

Institute of Hematology L. & A. Seragnoli, University of Bologna, Italy.

Pseudotumor cerebri or idiopathic intracranial hypertension is a neurological syndrome characterized by signs and symptoms of intracranial hypertension without clinical or radiological evidence of infective or space occupying lesions. Iatrogenic factors are frequent; in particular, cases of pseudotumor cerebri associated with all-trans-retinoic acid treatment in acute promyelocytic leukemia (APL) have been frequently described in pediatric patients. We report on a case observed in an older patient (young adult age) and give diagnostic and therapeutic guidelines.


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 Arch OphthalmolHome page
M. Colucciello
Pseudotumor Cerebri Induced by All-trans Retinoic Acid Treatment of Acute Promyelocytic Leukemia
Arch Ophthalmol, July 1, 2003; 121(7): 1064 - 1065.
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Copyright © 1996 by the Ferrata Storti Foundation.