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Haematologica, Vol 82, Issue 3, 362-363
Copyright © 1997 by Ferrata Storti Foundation

Case Reports

Granulocyte colony-stimulating factor-primed leukocyte transfusions in candida tropicalis fungemia in neutropenic patients

A Di Mario, S Sica, P Salutari, E Ortu La Barbera, R Marra, and G Leone

Hematology Chair, Universita Cattolica S. Cuore, Rome, Italy.

Optimal management of fungemia in neutropenic patients is still controversial. Several reports have already stressed the poor prognosis in invasive candidiasis (80% mortality in several reports). Therefore granulocyte transfusions would appear to be useful in the management of these infections. We report the use of rhG-CSF-primed granulocyte transfusions plus amphotericin B in two neutropenic patients who developed life-threatening systemic fungal infections. This approach was successful and both patients fully recovered from the infection.


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[Abstract] [Full Text] [PDF]


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Copyright © 1997 by the Ferrata Storti Foundation.