Haematologica, Vol 89, Issue 10, 1264-1266
Copyright © 2004 by Ferrata Storti Foundation
The effects of hydroxyurea on PRV-1 expression in patients with essential thrombocythemia and polycythemia vera
P Johansson,
A Ricksten,
C Wasslavik,
B Johansson,
and
B Andreasson
The study was designed to investigate the influence of hydroxyurea (HU) treatment on PRV-1 expression. Eighteen newly diagnosed patients with essential thrombocythemia (ET) or polycythemia vera (PV) were included. HU significantly increased PRV-1 gene expression in the early stage of treatment.