Haematologica
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Haematologica, Vol 89, Issue 10, 1266-1267
Copyright © 2004 by Ferrata Storti Foundation

Evaluation Studies

Molecular remission with arsenic trioxide in patients with newly diagnosed acute promyelocytic leukemia

B George, L Mathews, P Balasubramanian, RV Shaji, A Srivastava, and M Chandy

Thirty six APML patients achieving hematological remission with As2O3 were serially monitored using RT-PCR. Though only 5.5% achieved molecular remission at induction remission, 94.5% became negative during consolidation. At 20 months follow-up, 85% remain in remission but longer follow up studies are needed to monitor late relapses.




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Copyright © 2004 by the Ferrata Storti Foundation.