Haematologica, Vol 89, Issue 11, 1392-1394
Copyright © 2004 by Ferrata Storti Foundation
Latency of onset of de novo myelodysplastic syndromes
PS Wu,
AE Hay,
GE Thomas,
and
DT Bowen
The latency of onset of de novo myelodysplastic syndromes (MDS) is unknown. We report a retrospective analysis of blood counts from patients with MDS and acute myeloid leukemia (AML), and demonstrate temporal differences in rates of change of hemoglobin concentration and mean cell volume within 2-3 years of diagnosis, indicative of the earliest evidence of disease.