Haematologica
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Haematologica, Vol 89, Issue 11, 1394-1395
Copyright © 2004 by Ferrata Storti Foundation

Case Reports

Anagrelide-associated cardiomyopathy in polycythemia vera and essential thrombocythemia

DJ Jurgens, A Moreno-Aspitia, and A Tefferi

A comprehensive database inquiry at our institutions identified 11 patients with echocardiogram-documented idiopathic cardiomyopathy that post-dated a diagnosis of either polycythemia vera or essential thrombocythemia. Anagrelide therapy was temporally associated with the particular complication in 6 patients, all of whom experienced symptomatic and/or objective improvement after drug discontinuation.


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