Haematologica
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Haematologica, Vol 89, Issue 12, 1534-1536
Copyright © 2004 by Ferrata Storti Foundation

Clinical Trial

A reduced intensity conditioning regimen for allografting following autografting is feasible and has strong anti-myeloma activity

AM Carella, G Beltrami, MT Corsetti, P Scalzulli, AM Carella Jr, and P Musto

Sixteen patients with stage III multiple myeloma (MM) and a median age of 51 years were treated with autografting followed by reduced intensity conditioning allotransplantation (RICT). Nine patients are alive in remission at a median of 30 months after their transplants, one patient is alive in relapse and 6 patients died of progressive disease (5) or extensive chronic graft-versus-host disease, infections and progressive disease (1). We suggest that this two-step approach is feasible and it has strong anti-myeloma activity.




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Copyright © 2004 by the Ferrata Storti Foundation.