Haematologica
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Haematologica, Vol 89, Issue 3, 375-376
Copyright © 2004 by Ferrata Storti Foundation

Case Reports

Reduced-intensity allogeneic stem cell transplantation for renal cell carcinoma: in vivo evidence of a graft-versus-tumor effect

A Takami, H Asakura, K Koshida, M Namiki, and S Nakao

We report the cases of 3 patients with advanced renal cell carcinoma who underwent reduced-intensity allogeneic stem cell transplantation. In 2 partial responders, histologic analyses of metastases revealed prominent accumulation of CD8+ T cells and degenerative changes of clear cell carcinoma, suggestive of induction of tumor-specific cytotoxic T lymphocytes.




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Copyright © 2004 by the Ferrata Storti Foundation.