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Haematologica, Vol 91, Issue 10, 1436-1437
Copyright © 2006 by Ferrata Storti Foundation

Comparative Study

Effects of a Helicobacter pylori eradication regimen on anti-platelet autoantibody response in infected and uninfected patients with idiopathic thrombocytopenic purpura

A Asahi, M Kuwana, H Suzuki, T Hibi, Y Kawakami, and Y Ikeda

Thirty-seven patients with idiopathic thrombocytopenic purpura (ITP) were treated with a standard Helicobacter pylori eradication regimen irrespective of H. pylori infection. Our results indicate that platelet recovery results from the disappearance of H. pylori itself, and is mediated, in part, through suppression of anti-platelet autoantibody production.


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