Haematologica
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Haematologica, Vol 91, Issue 11, 1573-1574
Copyright © 2006 by Ferrata Storti Foundation

Comparative Study

A comparison of the in vitro cytotoxicity of daunorubicin and liposomal daunorubicin in pediatric acute leukemia

BF Goemans, CM Zwaan, D Reinhardt, BE Gibson, K Hahlen, and GJ Kaspers

Anthracyclines are effective in the treatment of leukemia, but their use is limited because of cardiotoxicity. Liposomal daunorubicin (L-DNR) is potentially less cardiotoxic than daunorubicin (DNR). We compared in vitro cytotoxicity in pediatric acute leukemia samples and found no significant differences between cytotoxicity of DNR and L-DNR.




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Copyright © 2006 by the Ferrata Storti Foundation.