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Haematologica, Vol 91, Issue 12, 1712-1713
Copyright © 2006 by Ferrata Storti Foundation

Letter

Myeloproliferative disease in the pathogenesis and survival of Budd-Chiari syndrome

JH Smalberg, SD Murad, E Braakman, PJ Valk, HL Janssen, and FW Leebeek

We studied the etiology, diagnosis and natural course of myeloproliferative disease (MPD) in 40 consecutive patients with Budd-Chiari syndrome (BCS). In 38% of the BCS patients with MPD another etiological factor was found. JAK2 mutation was present in 41% of the tested BCS patients. Survival was not significantly affected by the presence of MPD.


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